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It is estimated that there are fewer than 100 genetic diseases caused by single gene mutations in humans.

A) True
B) False

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There is a single gene that controls the ability to taste PTC paper. The ability to taste is dominant to the inability to taste. If you can taste the paper, it is very bitter. Which of the following genotypes can taste the paper?


A) only PP
B) both PP and Pp
C) both PP and pp
D) only Pp
E) only pp

F) A) and D)
G) A) and C)

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Unattached earlobes are a dominant trait in humans. Which phenotype does an individual with the genotype EE show?


A) Both earlobes are unattached.
B) Both earlobes are attached.
C) The right earlobe is attached and the left earlobe is unattached.
D) The right earlobe is unattached and the left earlobe is attached.
E) Both earlobes are extremely elongated.

F) A) and D)
G) All of the above

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A

An allele is to a gene as a locus is to a


A) gamete.
B) phenotype.
C) chromosome.
D) genotype.
E) unit of heredity.

F) A) and B)
G) B) and C)

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Which of the following represents a cross to determine if an individual is homozygous dominant or heterozygous?


A) Aa x aa
B) AA x AA
C) aa x aa
D) Aa x AA
E) Aa x Aa

F) C) and D)
G) A) and E)

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There is a trait with two alleles. One allele codes for blue while the other allele codes for yellow. If this trait is inherited in a codominant manner, what color will the offspring most likely be?


A) blue
B) yellow
C) green
D) blue-and-yellow striped
E) white

F) B) and E)
G) All of the above

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When describing people as "lactose intolerant," you are describing


A) their genotype.
B) their phenotype.
C) their alleles.
D) their genome.
E) none of these

F) A) and E)
G) B) and C)

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If you want to know the probability that tossing two coins will result in a particular outcome two heads, for example) , you use the


A) product rule.
B) sum rule.
C) punnett rule.
D) Bergman's rule.
E) genetics rule.

F) C) and D)
G) A) and B)

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Probability calculations in which the word "or" is used involve the product rule.

A) True
B) False

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In a pedigree, an affected male would be designated by


A) an open circle.
B) a shaded circle.
C) an open square.
D) a shaded square.
E) a square with a line through it.

F) B) and E)
G) A) and C)

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D

Can two parents that have a genetic disorder ever have a normal child?

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Which of the following is not a characteristic of an autosomal recessive disorder pedigree?


A) Heterozygotes have an affected phenotype.
B) Affected children can have unaffected parents.
C) Two affected parents will always have affected children.
D) Both males and females are affected with equal frequency.
E) Affected individuals with homozygous unaffected mates will have unaffected children. In an autosomal recessive disorder, heterozygotes have an unaffected phenotype.

F) B) and E)
G) A) and D)

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In a dihybrid cross, in which both parents are heterozygous for both traits, what is the probability that the offspring will exhibit both of the dominant phenotypes?


A) 1/16.
B) 3/16.
C) 6/16.
D) 9/16.
E) 1.

F) A) and B)
G) A) and E)

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The square that is used to make all the possible combinations of gametes is called a Punnett square.

A) True
B) False

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If the mother's genotype is aa, all of her eggs will be identical for this trait.

A) True
B) False

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Which of the following genotypes is heterozygous?


A) Aa
B) Ab
C) aB
D) ab
E) aa

F) All of the above
G) B) and C)

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Even though sickle-cell disease is inherited as an autosomal recessive disorder, the heterozygote can express some variation of the recessive phenotype.

A) True
B) False

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If a person with type B blood marries a person with type A blood, what phenotypes can their children be?


A) all type A
B) all type B
C) types A and O
D) types B and O
E) types A, B, O, and AB

F) A) and E)
G) A) and D)

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If a mother is a carrier for color-blindness and her husband is not color-blind, what are the probable genotypes of the children?


A) one normal daughter, one carrier daughter, one normal son, and one color-blind son
B) two normal daughters, one normal son, and one color-blind son
C) two carrier daughters, one normal son, and one color-blind son
D) one normal daughter, one carrier daughter, and two normal sons
E) one normal daughter, one carrier daughter, and two color-blind sons

F) B) and D)
G) B) and C)

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A

Which of the following traits/disorders is controlled by multiple genes?


A) skin color
B) Tay-Sachs disease
C) ABO blood type
D) familial hypercholesterolemia
E) curly hair

F) A) and B)
G) A) and C)

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