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Cancers of epithelial tissues are called


A) leukemias.
B) sarcomas.
C) carcinomas.
D) lymphomas.
E) blastomas.

F) A) and B)
G) B) and C)

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Which of the following is a side effect of radiation therapy that is not also a side effect of chemotherapy?


A) nausea, vomiting
B) dry, red, irritated skin and/or blisters
C) diarrhea
D) fatigue and weakness
E) weight loss and hair loss

F) A) and D)
G) A) and E)

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Which type of test is particularly useful in analyzing tumors in tissues surrounded by bone?


A) X-ray
B) CAT scan
C) MRI
D) PSA
E) Pap test

F) D) and E)
G) A) and D)

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C

The American Cancer Society publicizes seven warning signals, which spell out the word CAUTION. The "C" in CAUTION stands for change in


A) skin coloring.
B) bowel or bladder habits.
C) sensitivity to heat or cold.
D) sleep habits.
E) eating habits.

F) A) and D)
G) A) and E)

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Antiangiogenic drugs cause cytotoxic T cells to attack tumor cells.

A) True
B) False

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False

If a tumor suppressor gene becomes mutated, which of the following is not true?


A) Apoptosis is less likely to occur.
B) The cell cycle continues when it should not.
C) A "gain-of function" mutation has occurred.
D) Genes that encode enzymes that repair DNA are not turned on.
E) Genes that inhibit the cell cycle are not turned on.

F) None of the above
G) All of the above

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Which of the following is not a characteristic that distinguishes cancer cells from normal cells?


A) Cancer cells lack differentiation.
B) Cancer cells have abnormal nuclei.
C) Cancer cells use mitosis to divide.
D) Cancer cells have an unlimited potential to replicate.
E) Cancer cells form tumors.

F) B) and E)
G) B) and D)

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Which of the following is not a type of proto-oncogene?


A) the gene for cyclin D
B) growth factor receptor genes
C) the gene that codes for Ras proteins
D) growth factor genes
E) the gene for p53

F) B) and C)
G) B) and D)

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Which of the following factors can lead to cancer?


A) radiation
B) BRCA1 gene
C) tobacco smoke
D) radon gas
E) All of these can lead to cancer.

F) None of the above
G) C) and D)

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Unfortunately, the cancer in Ted's body has spread to multiple sites. Which is the most viable treatment option to handle Ted's cancer?


A) surgery
B) radiation therapy
C) chemotherapy
D) herbal therapy
E) vaccination

F) D) and E)
G) A) and D)

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Taxol is used to treat what type of cancer?


A) leukemia
B) lymphoma
C) testicular cancer
D) colon cancer
E) ovarian cancer

F) B) and D)
G) A) and D)

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A mole becomes suspicious when it is greater than 6 mm in diameter. How big is 6 mm approximately?


A) just barely visible, about the size of a pin prick
B) about the same as one of the letters in this question
C) about the size of a pencil eraser
D) about the size of a nickel
E) about the size of a quarter

F) A) and B)
G) None of the above

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List standard therapies and newer therapies for the treatment of cancer.

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The standard therapies for the treatment...

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Which of the following characteristics is not associated with metastasis?


A) The internal cytoskeleton is disorganized.
B) The cancer cells lack intact actin filament bundles.
C) Invasive cancer cells are abnormally shaped.
D) Cancer cells produce proteinase enzymes.
E) The low oxygen content in the middle of a tumor may turn on genes for angiogenesis.

F) A) and D)
G) A) and C)

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What type of cancer causes the most deaths in males?


A) prostate
B) lung and bronchus
C) colon and rectum
D) pancreas
E) esophagus

F) B) and D)
G) A) and D)

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Proto-oncogenes


A) code for proteins that promote the cell cycle.
B) promote apoptosis.
C) become tumor suppressor genes when mutated.
D) are considered "loss-of-function" mutations.
E) code for angiogenic growth factors.

F) None of the above
G) D) and E)

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A

The ends of chromosomes in human cells are "capped" with special repetitive DNA sequences called


A) radiata.
B) telomeres.
C) centromeres.
D) oncogenes.
E) suppressor genes.

F) C) and D)
G) A) and C)

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If you only inherit one mutated copy of BRCA1 and the other copy is normal, you will not develop breast cancer.

A) True
B) False

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Which of the following is not found in tobacco smoke?


A) vinyl chloride
B) N-nitrosonornicotine
C) asbestos
D) benzo[a]pyrene
E) mutagens

F) A) and E)
G) A) and B)

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Explain what CAUTION means as the acronym for the warning signs of cancer.

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C = change in bowel or bladder habits A ...

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